First human implants of the Full Sense™ Bariatric Device successfully completed Nov 3-4, 2008.

Recent results of the Full Sense™ Bariatric Device at the In3 East conference held in Boston, Mass

In3 East Conference Summary

The Full Sense™ Device is composed of an esophageal member, a cardiac disk and a connecting strut (Figure 1). It is placed via endoscopy in the esophageal / cardiac region of the stomach. It induces satiety by influencing the neurohormonal feedback mechanism. It augments fullness caused by food and simulates fullness in the absence of food by placing pressure in the distal esophagus and cardiac region of the stomach. The device is easily removable via endoscopy.

Figure 1. Full Sense™ Device

A series of studies demonstrate conclusively the ability of the Full Sense™ Device to cause significant weight loss in experimental animals.In four separate studies, animals lost approximately 1% of their body weight per day (Figure 2). Studies were halted after approximately 28 days due to weight loss exceeding 25% of their body weight, i.e., the animals were euthanized per Animal Care and Use Protocols.In spite of severe weight loss the animals were not lethargic and, in fact, were playful.

Figure 2. Composite data from four studies